ISIS.

IS, Otoko Demo Onna Demo Nai Sei (IS～男でも女でもない性～; lit. 'IS, The Gender That Is Neither Male nor Female') is a Japanese manga series written and illustrated by Chiyo Rokuhana. It originated as a one-shot published in Kodansha's josei manga magazine One More Kiss in 2003, before becoming a full series serialized in Kiss from 2004 to 2009; the series' chapters were collected into seventeen volumes. The story follows the pain and troubles intersex people go through in their lives, such as gaining acceptance for who they are and their inability to reproduce.